Gluconeogenesis in Cancer: Function and Regulation of PEPCK

Gluconeogenesis occurs in the liver and kidneys The gluconeogenesis pathway helps maintain blood glucose levels during fasting or low

Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as lactate,

gluconeogenesis Gluconeogenesis ADP + Pi GTP COO– C O Pyruvate carboxylase CH2 Phosphoenolpyruvate Oxaloacetate carboxykinase COO–Figure Reversal of the reaction of

gluconeogenesis Gluconeogenesis is defined as the net formation of glucose from non-carbohydrate precursors such as pyruvate, lactate, glycerol, and certain amino acids